VILNIUS TECH University Research Management System (CRIS)
Use this URL to cite this publication: https://hdl.handle.net/20.500.14911/113661

Does the shape of the electric pulse matter in electroporation?

Publication Type (CRIS)
Straipsnis Web of Science ir Scopus duomenų bazėje / Article in Web of Science and Scopus database (S1)
Publication Type (eLABa)
Straipsnis Web of Science DB / Web of Science DB article (S1)
VILNIUS TECH Research Priorities and Topics
Inovatyvios elektroninės sistemos / Innovative Electronic Systems (MC0505)
Lithuanian Intelligent Specialization
Sveikatos technologijos ir biotechnologijos / Health technologies and biotechnologies (L105)
Author(s)
AuthorAffiliation
Novickij, Vitalij  
Stiprių magnetinių laukų institutas / Institute of High Magnetic Fields (0555)  
Rembialkowska, Nina
Wroclaw Medical University
Szlasa, Wojciech
Wroclaw Medical University
Kulbacka, Julita
Wroclaw Medical University
Title
Does the shape of the electric pulse matter in electroporation?
[en]
Vitalij Novickij, Nina Rembialkowska, Wojciech Szlasa, Julita Kulbacka
Is part of
Frontiers in oncology
Published In
YearVolumeIssueStart PageEnd Page
2022
12
958128
1
12
Publisher
Lausanne : Frontiers Media SA
Publisher (trusted)
Frontiers Media SA
Referenced in Database(s)(DBs)
Science Citation Index Expanded (Web of Science)  
DOAJ  
SCOPUS  
PubMed  
Extent
p. 1-12
URI
URIAccess Rights
https://hdl.handle.net/20.500.14911/113661
https://www.frontiersin.org/articles/10.3389/fonc.2022.958128/full
Viso teksto dokumentas (atviroji prieiga) / Full Text Document (Open Access)
https://talpykla.elaba.lt/elaba-fedora/objects/elaba:140244352/datastreams/MAIN/content
DOI
Cited references
133
Science / Art Area
Technologijos mokslai / Technological sciences (T)
Field of Science / Art
Elektros ir elektronikos inžinerija / Electrical and electronic engineering (T001)
Biologija / Biology (N010)
Keywords (en)
Abstract (en)

Electric pulses are widely used in biology, medicine, industry, and food processing. Numerous studies indicate that electroporation (EP) is a pulse-dependent process, and the electric pulse shape and duration strongly determine permeabilization efficacy. EP protocols are precisely planned in terms of the size and charge of the molecules, which will be delivered to the cell. In reversible and irreversible EP applications, rectangular or sine, polar or bipolar pulses are commonly used. The usage of pulses of the asymmetric shape is still limited to high voltage and low voltage (HV/LV) sequences in the context of gene delivery, while EP-based applications of ultra-short asymmetric pulses are just starting to emerge. This review emphasizes the importance and role of the pulse shape for membrane permeabilization by EP.

Resource Type (COAR)
TextJournalJournal articleResearch article
Language
Anglų / English (en)
Country
Šveicarija / Switzerland (CH)
Description

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).

File(s)
ISSN (of the container)
2234-943X
eLABa ID
140244352
Funding(s)
Polish National Science Centre
Research Council of Lithuania
Access Rights
Atviroji prieiga / Open Access
Creative Commons License